\magnification=1200 \baselineskip=20pt \nopagenumbers \font\big=cmr12 scaled \magstep2 \centerline{\bf STANFORD UNIVERSITY} \centerline{\bf DEPARTMENT OF STATISTICS} \centerline{\big DEPARTMENTAL SEMINAR} \bigskip \baselineskip=12pt \centerline{4:15 p.m., Tuesday, April 1, 2003} \centerline{Sequoia Hall Room 200} \centerline{(Cookies at 3:45 in 1st Floor Lounge)} \bigskip \baselineskip=15pt \centerline{\sl Jack P.C. Kleijnen} \centerline{\sl Department of Information Systems and Management/Center for Economic Research (CentER)} \centerline{\sl Tilburg University (UvT), Tilburg, The Netherlands} \centerline{\sl http://center.kub.nl/staff/kleijnen/} \bigskip \centerline{\bf Application-driven Sequential Designs for Simulation Experiments: Kriging Metamodeling} \bigskip In this seminar I propose a novel method to select an experimental design for interpolation in simulation. Though I focus on Kriging in deterministic simulation, the method also applies to other types of metamodels (besides Kriging), and to stochastic simulation. I focus on simulations that require much computer time, so it is important to select a design with a small number of observations. The proposed method is therefore sequential. The novelty of the method is that it accounts for the specific input/output function of the particular simulation model at hand; i.e., the method is application-driven or customized. This customization is achieved through cross-validation and jackknifing. The new method is tested through two academic applications, which demonstrate that the method indeed gives better results than a design with a prefixed sample size. \bye